Testicular Cell Dynamics and Endocrine Signaling by Michael D. Griswold

Cover of: Testicular Cell Dynamics and Endocrine Signaling | Michael D. Griswold

Published by Blackwell Publishing Limited .

Written in English

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Subjects:

  • Molecular biology,
  • Science/Mathematics,
  • Medical,
  • Science,
  • Life Sciences - Biology - Microbiology,
  • Life Sciences - Cytology,
  • Urology,
  • CELL INTERACTION,
  • CELLULAR SIGNAL TRANSDUCTION,
  • SPERMATOGENESIS,
  • Science / Microbiology,
  • Endocrinology & Metabolism,
  • Cell Communication,
  • Congresses,
  • Signal Transduction,
  • Testis,
  • physiology

Edition Notes

Book details

SeriesAnnals of the New York Academy of Sciences
ContributionsMatthew P. Hardy (Editor)
The Physical Object
FormatPaperback
Number of Pages252
ID Numbers
Open LibraryOL9460776M
ISBN 101573315389
ISBN 109781573315388

Download Testicular Cell Dynamics and Endocrine Signaling

"Result of a conference entitled the XVIIIth North American Testis Workshop: Testicular Cell Dynamics and Endocrine Signaling held on March 30 Testicular Cell Dynamics and Endocrine Signaling book April 2,Seattle, Washington"--Page [v].

Description: ix, pages: illustrations: Contents: Development --Endocrine axis --Steroidogenesis --Spermatogenesis --Clinical correlates.

Series. ISBN: OCLC Number: Notes: "Result of a conference Testicular Cell Dynamics and Endocrine Signaling book the XVIIIth North American Testis Workshop: Testicular Cell Dynamics and Endocrine Signaling held on March 30 through April 2,Seattle, Washington"--Page [v]. Testicular Cell Dynamics and Endocrine Signaling, Volume by Matthew P.

Hardy,available at Book Depository with free delivery worldwide. Testicular Chromosome Structure and Gene Expression, Volume (Annals of the New York Academy of Sciences): focused on testicular cell dynamics and brought an influx of new information into the field of male reproduction.

Several laboratories have been actively investigating the endocrine signals between the germ and somatic cells of the. Author(s): Hardy,Matthew Phillip; Griswold,Michael D; North American Testis Workshop,(18th: Seattle, Wash.) Title(s): Testicular cell dynamics and.

Hardy M, Griswold M, eds. Testicular cell dynamics and endocrine signaling. Ann NY Acad Sci. ; Hormone Binding and Target Cell Activation in the Testis. Adult testicular function is modulated by a myriad of external factors and orchestrated by numerous hormones that together enable birds to adapt to and breed in diverse habitats worldwide.

These factors have generated a wide range of avian reproductive strategies, which has further shaped testicular structure and function. Book Description: Encyclopedia of Endocrine Diseases, Second Edition, comprehensively reviews the extensive spectrum of diseases and disorders that can occur within the endocrine system.

It serves as a useful and comprehensive source of information spanning the many and varied aspects of the endocrine end metabolic system. This book provides important information about the new insight into germ cell signaling and the genotoxic in vitro studies in testicular germ cells.

This book offers significant results about the origin, specification, and development of the female germ line in placental mammals and the germ cell tumors and their association with pregnancy. Description of the book "Bacterial Signaling": Providing a comprehensive insight into cellular signaling processes in bacteria, this is the first book to cover intercellular, transmembrane, as well as intra-cellular signaling and its relevance for biofilm formation, differentiation, host pathogen interactions, symbiotic relationships, chemotaxis and various stress responses.

Cryopreservation of testicular tissue before long-term testicular cell culture does not alter in vitro cell dynamics.

Fertil Steril ; 1,– The Workshop, published as volume of the Annals, focused on testicular cell dynamics and brought an influx of new information into the field of male reproduction.

Several laboratories have been actively investigating the endocrine signals between the germ and somatic cells of the testis, revealing previously unknown patterns of cell. Immunological, paracrine and endocrine aspects of testicular immune privilege Article Literature Review in Molecular and Cellular Endocrinology (1) April with 20 Reads.

Carouge D, Blanc V, Knoblaugh SE, Hunter RJ, Davidson NO, Nadeau JH () Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bias.

Proc Natl Acad Sci U S A (37):E–E PubMed Cited by: 2. Etiology of the Testicular Germ Cell Tumors The Testicular Dysgenesis Syndrome. In the last decade, there has been a continuous increase in the incidence of diseases of the male urogenital tract such as cryptorchidism, hypospadia, infertility, and testicular cancer.

This led to the development of the hypothesis that all these Author: Emmanuelle Martinot, Emmanuelle Martinot, Marine Baptissart, Marine Baptissart, Lauriane Sédes, Laur. Likewise, recent findings have shown that this signaling cascade also plays a critical role in the regulation of Sertoli-germ cell adhesion.

In this mini-review, we briefly discuss the regulatory role of each protein component of the NO/cGMP pathway in the context of testicular junction dynamics, as well as their importance in fertility and Cited by: 3.

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With this research and experience, we've uncovered an exact formula for getting results. The influence these endocrine hormones have on cell–cell signaling events is in part how hormones regulate gonadal function. The testis and ovary are also sites for the production of hormones.

These gonadal hormones have an endocrine role in regulating a wide variety of tissues in the body, but also can act in a paracrine manner within the. Stem cells are a group of undifferentiated cells having the dual ability to self-renew and differentiate into functional mature cells.

Somatic stem cells play essential roles in organogenesis and tissue maintenance, while germline stem cells (GSCs) can only produce gametes for reproduction (Li and Xie, ).In most of invertebrates and low vertebrates, both male and female animals have long.

Title: Nitric Oxide-cGMP Signaling: Its Role in Cell Junction Dynamics During Spermatogenesis VOLUME: 8 ISSUE: 1 Author(s):Dolores D.

Mruk, Oli Sarkar and Premendu P. Mathur Affiliation:Population Council, Center for Biomedical Research, York Avenue, New York, NYUSA. Keywords:Testis, tight junctions, adherens junctions, nitric oxide signaling pathwayCited by: 3.

The interaction between the immune and endocrine systems has long been recognized in vertebrates. In fish, it is known that the prevalence and intensity of such infections are higher in males than in females and probably related to sex steroid hormone levels.

In addition, the immune response in the fish gonad tissues is specifically regulated to prevent by: 3. Testicular cancer (TC) represents one of the most peculiar clinical challenges at present.

In fact, currently treatments are so effective ensuring a 5 years disease-free survival rate in nearly 95% of patients.

On the other hand however, TC represents the most frequent newly diagnosed form of cancer in men between the ages of 14 and 44 years, with an incidence ranging fromCited by: 1.

Androgens are key for pubertal development of the mammalian testis, a phenomenon that is tightly linked to Sertoli cell maturation. In this review, we discuss how androgen signaling affects Sertoli cell function and morphology by concomitantly inhibiting some processes and promoting others that contribute jointly to the completion of by: 3.

However, the testicular cell types expressing the THRs have not been clearly identified in fish. In mammals, THRs have been localized to SCs by different laboratories, while the staining in germ cells and in interstitial cells is debated (38, 39). Also in zebrafish, information on the testicular cell types expressing THRs is missing but is Cited by:   The system is tightly regulated and is maintained at a proper set-point by the negative feedback effects of testicular steroids and inhibin-B.

Testicular function is also influenced by multiple internal (paracrine and autocrine) and external (endocrine) environmental : Joseph P. Moore, Stephen J. Winters. Wang RS, Yeh S, Tzeng CR, Chang C.

"Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout. The Workshop, published as volume of the Annals, focused on testicular cell dynamics and brought an influx of new information into the field of male reproduction.

Several laboratories have been actively investigating the endocrine signals between the germ and somatic cells of the testis, revealing previously unknown patterns of cell signaling and cell-to-cell communication in male. Melissa Herman, Catherine Rivier, Activation of a Neural Brain-Testicular Pathway Rapidly Lowers Leydig Cell Levels of the Steroidogenic Acute Regulatory Protein and the Peripheral-Type Benzodiazepine Receptor while Increasing Levels of Neuronal Nitric Oxide Synthase, Endocrinology, VolumeIssue 1, 1 JanuaryPages –, https Cited by:   To investigate damage caused by NPs to testicular constituent cells, three in vitro studies evaluated the cytotoxic effects of different types of NPs on mouse Leydig TM3 cells and on the RTG-2 cell line.

The exposure of TM3 cells to increasing concentrations (0– μg/mL) of titanium dioxide NPs (TiO 2-NPs) induced a remarkable and dose-dependent reduction of cell viability [].Cited by: Encyclopedia of Endocrine Diseases, Second Edition, comprehensively reviews the extensive spectrum of diseases and disorders that can occur within the endocrine system.

It serves as a useful and comprehensive source of information spanning the many and varied aspects of the endocrine end metabolic system. Jeyaraj DA, Grossman G, Petrusz P () Dynamics of testicular germ cell apoptosis in normal mice and transgenic mice overexpressing rat androgen-binding protein.

Reprod Biol Endocrinol Johnsen SG () Maintenance of spermatogenesis induced by HMG treatment by means of continuous HCG treatment in hypogonadotrophic by: For a given sensory cell type, signaling motifs are rather uniform across phyla. By contrast, sperm from different species use diverse repertoires of sperm-specific signaling molecules and even closely related protein isoforms feature different properties and serve different functions.

This surprising diversity has consequences for strategies in fertilization research and it will take some Cited by: @article{osti_, title = {Lonidamine affects testicular steroid hormones in immature mice}, author = {Traina, Maria Elsa and Guarino, Maria and Natoli, Alessia and Romeo, Antonella and Urbani, Elisabetta}, abstractNote = {The effects on the hypothalamus-pituitary-testicular axis of the well-known antispermatogenic drug lonidamine (LND) has not been elucidated so far.

[Less] Dibutyl phthalate (DBP) has significant male reproductive toxicity, and the Sertoli cells are the target [More] Dibutyl phthalate (DBP) has significant male reproductive toxicity, and the Sertoli cells are the target cells of DBP.

This study was to investigate the injury effect induced by DBP on rat testicular Sertoli cells in vitro. Early in development at the time of gastrulation a small group of cells are "put aside" to later form oocytes and spermatozoa, these cells described as the primordial germ cells (PGCs).

The cells migrate initially through the primitive streak into the posterior endoderm that forms the hindgut, and from there later into the genital ridge that will be the site of the developing gonad.

Analytical construct of reversible desensitization of pituitary-testicular signaling: illustrative application in aging. Am J Physiol.;(2):R Keenan, DM, Roelfsema F, Veldhuis JD. Dose-response downregulation within the span of single interpulse intervals.

Am J Physiol.; (1):R Veldhuis JD, Keenan, DM, Pincus SM. Mammalian spermatogenesis is a high regulated biological process occurring in the seminiferous tubules in the testis.

The processing of this program requires delicate balance between cell proliferation, differentiation, apoptosis, and expedite cell interaction. Autophagy, an evolutionarily conserved cell reprograming machinery, had been shown to function as an important regulatory mechanism in Author: Zonghao Tang, Zhengchao Wang.

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

The androgen receptor is most closely related to the progesterone receptor, and progestins in higher Aliases: AR, AIS, AR8, DHTR, HUMARA, HYSP1.

INTRODUCTION. Steroid hormones act on target cells through their cognate receptors belonging to the intracellular steroid receptor superfamily (reviewed by Evans, ; Beato, ; Jensen, ).These are hormone-regulated transcription factors eliciting either induction or repression of specific genes (reviewed by Kumar and Tindall, ).Evidence, however, is accumulating that.

(Reproductive Biology & Clinical Embryology) ACADEMIC SCHEDULE Theory (Didactic) Lectures + Seminars + Journal Clubs – Semester I & II (2 hours / day) Practicals (Hands-on + Demo) – Semester I & II (first half) ( hours / day) Project + Dissertation – Semester II (later half), III & IV (first half).

A draft periodic table of cell types. Using the mouse as an example, a periodic table of cell types can be assembled based on current knowledge. The table is formatted from left to right based on development and/or differentiation trajectories, in which each element represents a cell type in the developmental by: 7.Androgen signaling is enriched within the preoptic area and hypothalamus, regions of the brain important for regulating endocrine functions and reproductive behaviors.

Therefore, expression of the putative zebrafish ar is expected to be robust in these brain regions as by: In the F l and F 2 generations, adverse effects on male fertility were seen at doses (dietary) as low as jig/kg/day.

c. Testicular Cancer i. Germ Cell Tumors A substantial body of evidence has accumulated indicating that the incidence of testicular cancer in men has increased significantly. The tumors are primarily germ cell in origin.

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